I've been getting red frames on any mp4 or mov files. Both filetypes have the h264 codec. Other comps with shape layers and text are unaffected. One more weird thing is that if I turn off hardware acceleration(under preferences>display) I get a display driver crash followed by AE crashing.
I upgraded to the latest version of QuickTime 7.7.9
I've cleared both caches through AE's preferences and by manually deleting files in the folders.
My workaround so far has been to use the previous version of AE and AME.
Windows 10 Pro (10.0.10586)
Intel Core i5-2500k CPU @3.30GHz
OpenGL Version 188.8.131.5299
AMD Radeon HD 6800 Series (2 linked with CrossFireX)
If it helps I can also show the windows error reports.
The red frames issue is something that has dogged Adobe for years, and despite claims of having fixed it, it is alive and well in every version of Premiere or After Effects I've used. I don't run into it often, but when I do my usual fix is to convert the media to something else and edit that. It's inconvenient most times, to say the least. I've had it happen to numerous codecs: ProRes, H.264, XDCAM, etc.
I've heard it stems from the software filling in missing frames in order to match the correct clip length, but I don't know how true that is.
It is reall annoying. I have been using 2015.2 without problems and after the update I get the random red frames on the mpg (h.264 codec) too. Rolled back to 2014 and there are no problems for me. Next time only updating if I have to.