When I'm doing work for broadcast (which is not so much anymore - but it was my only constraint for 15 years or so), I generally cheat my graphics up to half way through Title Safe - of course, this all depends upon the composition, and sometimes I'll keep my text constraints right up to the Title Safe lines, and sometimes I'll cheat them out.
With things like bugs and lower thirds, I generally take the bugs almost up to the Action Safe line, and the lower third container will extent all the way to the raster edge. That said, my text lines in the lower third will all stay within Title Safe, but if, for example, I have a logo bug on the lower third, I feel free to cheat it into the Title Safe area.
Of course, with web stuff, all bets are off, although I respect the Title Safe boundary for web creation, since nothing looks worse than text or graphical elements which are too close to the raster frame. It's also good to bear in mind how the final delivery is going to be dealt with - if you're doing an HD production, and the broadcast station decides to do a center cut (their specs will usually specify "Center Cut Safe" for graphics), that beautiful layout you worked so hard to get right in HD is going to get chopped to 4:3.
Joe Bourke
Owner/Creative Director
Bourke Media
http://www.bourkemedia.com