Well that's a pretty good question. The applications RED and BLUE are quite different in terms of their needs and what it takes to make them operate in a speedy manor. Let's start with RED - RED is a CPU based 2.5D compositing, titling and special effects application. It works best on the machines equipped with the latest multi-processors with several Gb's of RAM and a good amount of free disc space. Blue is a GPU based real-time 3D compositing, titling and special effects application. It needs a very fast graphics card, preferably manufactured by Nvidia, a couple of Gb's of RAM and a good amount of free disc space.
So what configuration to recommend to run both applications on the same system? I would think you should go for a multi-processor equipped Windows system with a Quadro FX graphics card (4000/4500 is a great choice), at least 2 Gb of RAM (4 is better) and a striped raid array.