The only question you'll have to answer is what your export settings are set to. You encode everything to the lowest common denominator - ProRes422. Or you can export your final timeline as ProRes(HQ) which will convert all the standard ProRes clips in your timeline to (HQ). You're call in the end....which way you go may depend on the type of footage you have and if it has other post-processes to go through (graphics, color grading, etc.).