Not really. Particular's particles are more like 2.5 D and do not react to light except for the cloudlet and smokelet type which derive their shadow info from 1 dedicated light and even that is not real 3D lighting. And before you complain: no, there is no easy way around that even in a 3D program. Most 3D progs use the same simple approach for their standard particles or even just simple 2D sprites which don't react to light properly. Back onto your' case I'd say your only option is to use multiple layers of Particular and adjust the manually so they kinda reflect your scene lighting. If depth-sort them properly, this shouldn't be too noticable. The other option is to use pre-compositions that contain halfway properly shaded version of your Amoeba or whatever as custom particles for particular.