Haven't heard this one before (and just when I was starting to think I've seen it all).
On a major title I would consult a testing facility to find out the install-base of the player, and if it's considerable, run different scenarios with audio - pcm, dd, dts at different rates to see if and what changes. Otherwise, I would run the audio on a bunch of brand-name players (at least one from each major manufacturer), and if they're all good, I wouldn't worry too much about it.
Thanks for the quick reply Max. That's good advice. I'm glad to hear that it's a rare occurence. This disc has been in a whole bunch of players with only this one, a Supersonic (?!), as the bad egg. Got it at a casino as a free prize.