I have had a RAID-0 array for about five years now. I use a High Point Technologies raid card and can hook up 6 drives but still only use 2. If you want to go that way I will help you as much as I can.
Pretty straight forward, install the card, install drives add drivers and software, set up array then format all your drives as one.
I still have my OS, XP Pro on a seperate drive.