Supermicro makes some great MOBOs. I assume that should work just fine.
just makes sure your case will be big enough for this card and the MOBO is designed to take that specific card in it's specific slot without having items sticking out of the board that will prevent you from fully seating the card into the slot.
But I highly suggest you go to matrox's website and find their suggested/ recommended computer hardware list. (and known non compatible hardware)
your post left out the most important part: graphic display card. research that before purchasing!!!!!!!!!!!