Did you render and export it out to a pro res file?
Unclear if you are talking about rendering a bunch of effects on the timeline or a full export.
If just multiple effects, you can fix just what you need and it wont disturb the others unless, you have another element that connects them all, like a lower third super or an adjustment layer and still the smart rendering works pretty well.
IF it is a whole timeline export, No. You are going to have to re-export out that file.
IF the timeline is rendered, choose to USE PREVIEW FILES when exporting and it will speed up your export.