The Web Client should support Chrome and IE8 and IE9, though I don't know if older versions of IE are supported.
You might need to adjust the option whether to use HTML5 video or the QuickTime plugin between the different browsers. We plan to publish recommended proxy settings and a list of supported browsers in the near future.
Thanks Rolf, I will pass this along. I have been working to finalise a photo and project library about to extend to video and webclient use, after a bit of a last minute flurry we got it all happening with the server permissions etc and it's looking great! Cheers Sava