I installed Leopard on a FW drive a few weeks ago, and Photoshop CS2 a few days ago. (I'm on an iMac.) Worked fine for a while and then the font I was using, Palatino, and I don't know what other fonts, went missing. Fonts could not be reloaded because of a program error. I rebooted and the font was back. But it has since disappeared again and seems to be gone for good. Repairing Permissions doesn't help.
The font does not turn up in a search of the drive--but then again the OSX search function has always been buggy--it doesn't show the font on the internal drive either, even though it's there.