I have a 9.5 GB .mov file that is 45 minutes in length that I would like to compress for web and maintain high quality. I want to upload it to Vimeo which means it needs to be smaller than 500 MB. Are there any ways of doing this using Apple Compressor, MPEG Streamclip, etc. ?
IF youre not afraid of some trial and error time, you might be able to maintain large portion of quality in an .mp4 (h.264) compression using a bitrate below 4.0, say 3.0 in SD, for upload.
If youre able - not through the quicktime codec, but straight .mp4 - it should land you around 12mb/minute = roughly 540mb for the 45min, but it very much depends on the amount and change of colors in your video.