What's your system specs?
Im guessing you would need at least 3-4 fast drives in a performance raid
to be able to play this back without dropping frames.
There is very little if any benefit to using the "none" compression option. Pick a lossless
codec like animation or Prores. The quality will be the same, the file size will be much smaller.
Not to say that you will be able to play the quicktime back on your system without dropping
frames if you render to a lossless codec. Your system may not be up to the task if your operating
off of a single drive.
H.264 is an interframe codec and not sutable for editing or working with in AE.
Dave LaRonde explains:
Dave's Stock Answer #1:
If the footage you imported into AE is any kind of the following -- footage in an HDV acquisition codec, MPEG1, MPEG2, AVCHD, mp4, mts, m2t, H.261 or H.264 -- you need to convert it to a different codec.
These kinds of footage use temporal, or interframe compression. They have keyframes at regular intervals, containing complete frame information. However, the frames in between do NOT have complete information. Interframe codecs toss out duplicated information.
In order to maintain peak rendering efficiency, AE needs complete information for each and every frame. But because these kinds of footage contain only partial information, AE freaks out, resulting in a wide variety of problems.
Dave's Stock Answer #3:
Don't use AE to compress files for final delivery. The various compressors are there only to make quick 'n dirty files showing a project's progress to producers, clients, the kids, etc. AE is incapable of doing multipass encoding, a crucial feature that greatly improves the image quality of H.264 and MPEG-type files in particular.
Render a high-quality file from AE, and use a different application to do the compression. Popular ones are Adobe Media Encoder, Sorenson Squeeze and Apple's Compressor, which comes bundled with Final Cut Suite. Even compressing in Quicktime Pro is better than compressing in AE.
Making good-looking compressed files is almost as much an art as it is a science. It is NOT straightforward at all. I recommend asking a few questions at the COW's Compression Techniques forum.