There are plugins designed for skin softening and cleanup that work by selecting the color of the targetted skin, then blurring and lowering the contrast. Beauty Box comes to mind.
Otherwise check out David Torno’s work on the Pistol Youth video for “In My Eyes.” He used After Effects together with mocha-AE to replace the faces of the Golden Girls with the face of Bradley Hanan Carter of Pistol Youth.
Thanks but this is not what Im looking for. I need to replace parts with acne (many small blemishes) or track clones to this spesific area. It could help if I figured out how to use the mask vertex data that I have (I have a mask that follows the skin area) and apply that to a null object.