Nothing can enhance the efficiency and simplicity of the editing process more than a solid familiarity of the software being used. Premiere lets you change the interface to suit your desires - use that.
I loved Avid Media Composer. I absolutely loved it, but Adobe CS looked interesting. When I decided to switch to Premiere CS, it was rough. The interface was so different, the method was foreign. However, the more I used it, the better it felt. Then, at one point I had to start up Avid to re-animate an old project, and it felt like I was editing in a block of stone with a hammer and chisel. I needed to have the user manual on the desk at all times to look up the most mundane techniques.
So...give it time.
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"98% of all computer issues can be solved by simply pressing 'F1'."
Steve Brame
creative illusions Productions