[Sam Caino] "In the meantime, I am going to recommend my friend use the no-compression render to break up this large file, see how that works."
I would not work with uncompressed video unless you have a RAID to deal with the throughput of the incredibly large files it will produce.
A good intermediary codec for the PC is CineForm. It edits easily in Vegas. Of course, CineForm is not free but it's well worth the money. If your friend is looking for a free solution then Avid DNxHD is a good QuickTime solution that has the added advantage that it is portable across PC and Mac. Sony MXF is also another format that edits easily in Vegas.
Having said all that... MPEG2 should edit easily in Vegas as well so maybe his computer isn't up to the task?
~jr
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