Start by telling us exactly what version of Premiere Pro you're using.
If you're using Premiere Pro CS5 (5.0.0),
installed the latest updates. They fix a lot problems, including some audio/video synch bugs. After applying the updates, clear out your
media cache, since you need to reconform and reindex your files for one of these fixes to take effect.
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Todd Kopriva, Adobe Systems Incorporated
Technical Support for professional video software
After Effects Help & Support
Premiere Pro Help & Support
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