If its static what you do is export a still from when the door is in focus and bring that into Photoshop. Then in Photoshop you clone out the handle. Now pull that back into After Effects and put a mask on the layer so that it is only on top of the handle part of the door.
At this point the handle has disappeared! But now for the annoying part... You need to match the rack focus by putting a "Camera Lens Blur" plug-in on your .psd layer and tweaking the settings until it looks right. Everything up to this point should take you 15 minutes max, but animating your rack focus can take a bit - depending on how picky you are.
Possibly check out this video to see if it helps you at all:
http://www.videocopilot.net/theblogshow3/nice-rack-focus/
Hopefully that was clear...
- Spencer