Well, in my case, mine actually is my NLE Workstation, but if you wanted it to be separate storage, you could connect it quite a few different ways. Gigabit Ethernet, Firewire 800, Firewire400 eSata, Sata, even SCSI. I prefer to work with files directly on my system. I'd just use it to store files long term. In response to some of the other replys, yes, you would want to use a UPS, and yes, static electricity is a concern, but all you really need to do is ground your case to the ground in an outlet and then you won't have any ESD concerns. Basically I'm suggesting what apples sales
http://www.apple.com/xserve/raid/ , but just doing it for half as much. Of course their method has those cool little apple's on them, but I don't personally think that is worth 6K :) I do know that apple's xserve is reliable since that is what one of the local tv stations uses for 4:2:2 and 4:4:4 HD editing. The other nice thing about the CM Stacker (and no, I don't work for them) and one of the reasons I bought mine, is that there is room for a lot of hard drives and a lot of DVD/HD-DVD/Blu-Ray drives and room for a pcmcia adapter for the hvx200