Media Missing, Unexpected Quits and the Dreaded PINK in my bins!

I have the Media 100 1.1.2 Suite. Long time media 100 user and just updated to this new system when I got a new desktop.
Having all kinds of problems. Error - 18004 then error 19004, unexpected quits, searching for media..Media disappearing from programs, the whole 9 yards.
My latest, and as of yet unfixable, problem is that when I open the project that I've been working on my media comes up in the bins the dreaded PINK. No pretty picture, just a pink bkgd.
I've looked for corrupt media in my drives and can find nothing of the like. I have dumped the preferences and everything is up to date as far as drivers go.
Full disclosure...I'm running the trial version as I wanted to make sure that the software was solid before I ponied up $1500
Running... Black Magic Deck Link HD Extreme
Mac OX 10.6.2 Quad Core 2 x 2,66 GHZ with 6 GB of ram

Any help is appreciated, Wickham, Are you out there?
Tell me something Good!

Mike Perkins