Best setting for long format

Hey guys, nice to see this Sorenson forum. I'm helping to prepare a video based website that is going to involve a ton of training videos, shot in HD, and a lot of them will be like 30 minutes long. I want to keep the HD aspect ratio, but am wondering what is the best compression setting to use for these to stream. I'm thinking about using the youtube (1080) preset that is on the exchange, but I thought I might ask here to see if anybody has any better suggestions. Thanks