Hi;
Xavier, this is the age-old question - how to get the smallest possible rendered video without sacrificing quality.
Many of us, including me, just pick one of the built-in Vegas codecs and let Vegas do it's thing. NTSC, BluRay, h.264 for Youtube, etc.
There are others who disdain these easy methods and do more complicated things. The "Handbrake" methods come to mind. Nick Hope is a big proponent of them, and his vids looks amazing.
Some more info can be found here:
http://www.jazzythedog.com/testing/DNxHD/HD-Guide.aspx
Have fun!
Steve
Win7 Pro X64 on Dell T3400, MultiTB SATA, 8GB RAM, nVidea FX 570, Vegas 10e (and 11) x64 DVDA 5.2(build 133) Sony HDR-CX550V