Sorry to hear about your lost work. Without having more specific details, like the full error text, it's hard to know exactly what caused your crash. I'm speculating that what you saw was a BSOD resulting from an IRQ request. This is often the result of a driver that's behaving badly. Audition's performance is heavily reliant on your audio hardware and drivers. I would check to see if an updated driver is available for your audio hardware.
There are other general troubleshooting suggestions in this document that may be helpful in your case.
http://kb2.adobe.com/cps/825/cpsid_82500.html
