Media 100 Suite -
http://www.borisfx.com/media100/index.php
I'm not alone when I say it's the easiest to learn. Using the link above, on the right hand side of their page you will see "Video Tutorials" - click on that and then watch "Getting Started with Media 100 Suite" to get an idea of how it works (of course you can also check out any of their other tutorials). Download a free, fully functional 14-day trial version to see exactly how it will work on your system. The COW has a Media 100 pasture (forum) for help.
Good luck!
Gary
This is me - this is what I do -
http://web.mac.com/garymmw 
