DVD Playback is Different on the Computer than DVD Player

I'm using Encore for a DVD project for work. When we go to review the DVD there are major differences between playing on the computer vs on a DVD player.

On the computer, everything seems to work fine, but when you put it on the DVD player, the color of the video shifts around, buttons don't work, video skips or doesn't play at all and some audio drops out.

Does anybody else have similar issues Encore, or could it be something that I am doing wrong?