Re: Live Streaming solution - HD streaming hardware and software

Personally I'd consider Blackmagic Quad (cross platform) or Matrox Multi (MacPro) with Telestream Wirecast. It'll see all four HD inputs simultaneously for Picture in Picture if you want. Make sure you have a higher end computer for that. I'd think 8 or 12 core Xeon to be safe.

ATEM would certainly works as well but you'd still need a Video I/O box and computer to input and encode.

With Wirecast I've used Skype Group Video account and Wirecast's Desktop Presenter feature to bring everyone in to the live stream with their video. It's good for virtual panel discussions. You can crop each participant so they can have solo shots. If you're taking one call at a time then a standard Skype account will work. I do this for call in interviews with audience and/or guests.